large or important enough to have an effect or to be noticed

The fact that her remarks were leaked to the media in advance is highly significant.

It is significant that he changed his will only days before his death.

This year's event is particularly significant as it takes place on the centenary of his birth.

rituals which are deeply significant to Christians

November 16th will always be an especially significant day for us, thanks to the birth of our second grandchild.

having a special or secret meaning that is not understood by everyone

a significant look/smile

LEARNit Dictionary