to suppose that something is true, although you do not have actual proof

to accept that something is true until it is shown not to be true, especially in court

Twelve passengers are missing, presumed dead.

In English law, a person is presumed innocent until proved guilty.

We must presume innocence until we have proof of guilt.

We must presume them to be innocent until we have proof of guilt.

to accept something as true or existing and to act on that basis

The course seems to presume some previous knowledge of the subject.

to behave in a way that shows a lack of respect by doing something that you have no right to do

I wouldn't presume to tell you how to run your own business.

LEARNit Dictionary