to become extremely tired or sick by working too hard over a period of time; to make somebody do this
از پا افتادن, تحلیل رفتن, خسته شدن کامل, بی حال شدن از کار زیاد
If he doesn't stop working so hard, he'll burn himself out.
By the age of 25 she was completely burned out and retired from the sport.
see also burnt-out(2)